甘油二异硬脂酸酯属于非禁限性物质，用于制备化妆品乳液、无水唇膏及软膏的油包水型乳化剂。该成分的致痘风险等级参考自Fulton， J. E. Comedogenicity and irritancy of commonly used ingredients in skin care products. J Soc Cosmet Chem 43， 321 - 333 (1989).