羧甲基脱乙酰壳多糖
CARBOXYMETHYL CHITOSAN
羧甲基脱乙酰壳多糖
Cas No:83512-85-0
Safety
羧甲基脱乙酰壳多糖的医用别名为羧甲基壳聚糖,在细胞抗炎实验中,可以显著降低IL6及TNFα水平,人体实验中也体现出抗炎的作用;动物实验促进皮肤角质层形成细胞生成,加速皮肤皮表角质层修复,表明其具有皮肤屏障修复功能;可以快速缓解由组胺引起皮肤瘙痒,显著缓解由皮肤过敏引起的刺痛感,动物实验已证实其止痒效果。 Pan M , Liu H T , Peng W , et al. Chitosan oligosaccharides inhibit LPS-induced over-expression of IL-6 and TNF-α in RAW264.7 macrophage cells through blockade of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling pathways - ScienceDirect[J]. Carbohydrate Polymers, 2011, 84(4):1391-1398. Minagawa T , Okamura Y , Shigemasa Y , et al. Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing[J]. Carbohydrate Polymers, 2007, 67(4):640-644.