琥珀酸二乙基己酯在化妆品中常作皮肤调理剂、成膜剂、增塑剂使用。该成分的致痘风险等级参考自Fulton， J. E. Comedogenicity and irritancy of commonly used ingredients in skin care products. J Soc Cosmet Chem 43， 321 - 333 (1989).